A new study has shed light on the troubling connection between psychedelic use and the increased risk of schizophrenia. With hallucinogens gaining popularity across North America for recreational and experimental purposes, this research serves as a critical warning about the potential dangers associated with these substances.

A Startling Link to Schizophrenia

Researchers, analysing data from over 9.2 million individuals in Ontario, Canada, found that individuals who visited emergency departments (EDs) due to hallucinogen-related issues were at a significantly increased risk of developing schizophrenia. The study revealed that these individuals faced a 21-fold higher likelihood of a schizophrenia diagnosis compared to the general population. Even after accounting for other mental health conditions and substance use, the risk remained 3.5 times higher. “Our findings underscore a concerning link between hallucinogen use that requires care in the emergency room and increased risk of schizophrenia,” says Dr. Daniel Myran from the University of Ottawa.

Additionally, a study highlighted in Psychiatric Times notes that “25% of people with substance-induced psychosis had a follow-up diagnosis of schizophrenia,” with hallucinogens being one of the substances with a higher risk of transition

Hallucinogens such as psilocybin, LSD, DMT (Ayahuasca), and MDMA (Ecstasy) may seem appealing to some, but the long-term risks cannot be ignored. The study found that within three years of an ED visit involving these substances, 4% of individuals were diagnosed with schizophrenia, compared to just 0.15% of the general population.

The Growing Trend

Between 2013 and 2021, the rates of ED visits tied to hallucinogens rose by a staggering 86%. Alarmingly, individuals using hallucinogens were at much higher risk of developing schizophrenia than those with ED visits related to alcohol or cannabis use.

Dr. Daniel Myran, a leading researcher from the University of Ottawa, stressed the severity of these findings. He stated, “Our findings underscore a concerning link between hallucinogen use that requires care in the emergency room and increased risk of schizophrenia.” While there may be ongoing discussions about potential therapeutic uses for psychedelics, this research highlights the alarming gaps in knowledge about the risks.

Long-Lasting Impacts

The study provides a stark reminder of the potential for lasting harm from hallucinogen use. Beyond the immediate dangers leading to emergency visits, there is the chilling possibility of triggering life-altering mental illnesses such as schizophrenia, especially in individuals predisposed to psychosis. This is particularly concerning given the growing popularity of psychedelics.

Dr. Marco Solmi from the University of Ottawa further emphasised the need to take these findings seriously. “It is important that we are able to identify those at risk of developing serious adverse events from psychedelics,” he noted, calling for more public awareness about these dangers.

A Cautionary Outlook

While proponents of psychedelics often highlight their potential for use in clinical therapy, it is clear from these findings that such substances can carry grave risks. This is especially true outside strictly controlled clinical environments. The dangers are real, and the consequences can be severe—not just for individuals, but for their families and communities.

This study is a powerful reminder that hallucinogens and other drugs can have serious, even deadly, repercussions. Decisions regarding substance use should be informed by a full understanding of the risks and their potential to impact lives irreversibly. By prioritising education and awareness, we can work towards fostering healthier, safer choices for everyone.

Source: EurekAlert