A new analysis highlights a worrying trend in the UK—liver cancer death rates have nearly doubled over the past two decades, making it the fastest-rising cause of cancer mortality. Around 81,300 people have lost their lives to the disease in the past 20 years, and concerning projections estimate approximately 135,000 deaths by 2040. Unlike most cancers, where mortality rates are decreasing, liver cancer’s death rate is expected to rise an additional 10% in the coming years.

Liver cancer is significantly driven by preventable factors. Excess weight and obesity contribute to nearly 25% of cases, while smoking accounts for over 20%. Alcohol use and lifestyle habits among older generations have also been linked with the increase in liver cancer cases and deaths across these age groups. Combating these risk factors is critical to slowing the disease’s upward trajectory.

Sophia Lowes, a senior health information manager at Cancer Research UK, emphasised, “Keeping a healthy weight, stopping smoking, and cutting back on alcohol can reduce your risk of cancer.” Developing healthier routines can play a key role in reducing the risk of this deadly disease.

Furthermore, early detection of liver cancer dramatically increases the chances of successful treatment and survival. “Early detection saves lives,” a widely used phrase in cancer awareness campaigns, underscores the significance of recognising symptoms early and getting screened (Source: Brio Medical).

While liver cancer can be challenging to treat, catching it early offers real hope. Unexplained weight loss, yellowing of the skin and eyes, itching, nausea, or a swollen abdomen are often signs to look out for. Lowes advises, “Whether it’s one of these symptoms or not, you know your body best. If you spot something unusual, see your doctor. It’s better to get it checked, even if it’s not cancer.” Currently, survival rates remain painfully low, with just 13% of people diagnosed in England surviving beyond five years.

Groundbreaking research could change this trajectory. Projects like HUNTER aim to revolutionise liver cancer treatment through advanced immunotherapy. Over £20 million has been invested in liver cancer research, focusing on prevention, detection, and treatment. “A multidisciplinary approach is mandatory to ensure an optimal diagnosis and staging of hepatocellular carcinoma, planning of curative and therapeutic options,” a panel of experts noted during the 24th World Gastrointestinal Cancer Congress (Source: National Centre for Biotechnology Information).

Strong policy changes also play an essential role. Dr Ian Walker of Cancer Research UK stated, “The UK Government has the opportunity to help people live more healthily, which could save thousands of lives, and save the NHS millions.” Initiatives like the Tobacco and Vapes Bill seek to curb smoking, a key risk factor, and create a healthier future for all.

By raising awareness, funding cutting-edge research, and implementing supportive policies, we can turn the tide on liver cancer and protect thousands of lives in the years to come.

Source: Cancer Research UK