The University of Florida conducted a study exploring the potential of synthetic oxytocin, often called the “cuddle hormone,” in aiding opioid addiction recovery. The research aimed to determine if oxytocin could be employed in managing acute pain while avoiding the risks associated with opioid use, particularly in older adults. Funded by the National Institutes of Health, this two-year study involves an interdisciplinary team analysing oxytocin’s effects on pain management and its potential to reduce reliance on opioids.

Participants aged 55 to 85, with histories of opioid use, were involved in a double-blind, randomised, placebo-controlled study. They received oxytocin via nasal spray or a placebo following oral oxycodone. Their responses to the substances, including cognitive and affective changes, were observed, and pain levels were measured using mechanical and thermal stimuli.

The study suggests that utilising oxytocin in place of opioids could effectively manage pain without the associated risks of addiction. This innovative approach offers a promising and safer alternative to traditional pain management strategies, presenting synthetic oxytocin as a pivotal element in addressing the ongoing opioid crisis in the U.S., aiming towards a future free from opioid dependency.

Source: News-Medical.Net